Porcine transmissible gastroenteritis
Can occur in pigs of all ages, high piglet mortality within 10 days, more than 5 weeks old pig mortality is low, the larger adult pigs or pig almost no deaths. To prevent secondary infection, for piglets under 2 weeks, may be appropriate to use antibiotics: chloramphenicol as intramuscular injection every 10 to 30 mg kg body weight twice a day; Sulfaguanidine 0.5 to 4.0 g, bismuth nitrate 1 to 5 g, 1 to 4 grams of baking soda mixed orally.
Transmissible Gastroenteritis is an acute intestinal infectious diseases in pigs. The clinical features are diarrhea, vomiting and dehydration. Can occur in pigs of all ages, high piglet mortality within 10 days, more than 5 weeks old pig mortality is low, the larger adult pigs or pig almost no deaths.
1. Pathogen
The swine pathogens for the coronavirus family of transmissible gastroenteritis virus.
2. Popular features
All ages are susceptible pigs, piglets within 10 days of morbidity and mortality are high, piglets, fattening pigs and adult pigs symptoms of mild, most naturally recover. Infected pigs and pigs are the main source of infection, they shed virus, contaminated feed, water, air and utensils from the feces, milk, nasal fluid, from the digestive tract and respiratory tract invade susceptible pigs. The disease mostly occurs in winter, is not easy to pop in the hot summer months. New outbreak occurs in epidemic form, spread rapidly in a week can be spread to pigs in each age group. It was in the old endemic or epidemic intermittent occurrence, the incidence little pigs, 10 days to 6 weeks of age, piglets easy to get sick, and the implicit rate of infection is very high.
3. Clinical symptoms
Incubation period: 12 to 24 hours piglets, pigs 2-4 days.
(1) Piglets: first sudden vomiting, followed by severe watery diarrhea. Vomiting occurred after breastfeeding. Diarrhea is white or yellow-green, with a small piece of undigested curd, fetid. In the pathogenesis of late, due to dehydration, fecal slightly sticky, reduce weight quickly, the temperature drops, often in two to seven days after the onset of death, resistance to over-pig grow more slowly. Piglet mortality within 5 days after birth often 100%.
(2) Finishing Pigs: The incidence of close to 100%. Sudden onset of watery diarrhea, loss of appetite, weakness, diarrhea, stool gray or dark brown, containing a small amount of undigested food. In the early days of diarrhea, occasional vomiting. Course of about one week. During the onset of weight gain slowed down.
(3) adult pigs: no disease after infection. Part pigs showed mild watery diarrhea, or a moment of soft stools. No significant effect on body weight.
(4) sow: sow with piglets often onset. Some of lactating sows after onset, showing a high degree of weakness, fever, lactation stops, vomiting, loss of appetite, severe diarrhea. Pregnant sows symptoms are often not obvious, or only mild symptoms.
4. Anatomic pathology
The main pathological changes in the stomach and small intestine. Piglets often swollen stomach is full, stranded there undigested curd. 3-day-old piglets, there diverticular bleeding spots under the mucosa of the stomach about 50% of the surface of the diaphragm. Swelling of the small intestine, there is foamy liquid and undigested curd, intestinal villous atrophy, intestinal wall thinning, see the milky chyle in mesenteric lymph duct. Intestinal mucosa severe bleeding.
5. Diagnosis
Piglets within 2 weeks of high incidence and high mortality, accompanied by vomiting, watery diarrhea and rapid dehydration may initially diagnosed.
6. Prevention
First of all, pay attention to management, in late autumn to early spring between the cold season, not the introduction of infected pigs, to prevent persons, animals, utensils spread of the disease. Secondly, the disease often in the farm, use the following three methods to control the incidence of this disease. First, pregnant sows in prenatal 45 days and 15 days, with TGE attenuated intranasal vaccine muscle and 1 ml each vaccination to generate sufficient immunity, so that breast-fed piglets obtained by antibodies to produce the effect of passive immunization; or in the piglets born to non-pathogenic attenuated vaccine orally immunized piglets per 1 ml oral, to produce active immunity. The second is to change the management method to interrupt the infection environments, such as changing the plan calving time, the "all in all out." The third is the anticoagulant Rehabilitation pigs or hyperimmune serum, daily oral administration of 10 ml, once every three days, for the novice piglets have some control effect.
7. Swine Disease Prevention
Make recipes solution under piglets Beverage: NaCl 3.5 g, KCl 1.5 g bicarbonate 2.5 g glucose 20 grams of regular water 1000 ml. To prevent secondary infection, for piglets under 2 weeks, may be appropriate to use antibiotics: chloramphenicol as intramuscular injection every 10 to 30 mg kg body weight twice a day; Sulfaguanidine 0.5 to 4.0 g, bismuth nitrate 1 to 5 g, 1 to 4 grams of baking soda mixed orally.
