Fu Rui Di
The main components of florfenicol.
¡¾Properties¡¿ white or off-white powder.
Pharmacological effects pharmacodynamics florfenicol belong amphenicols broad-spectrum antibiotics, a variety of Gram-positive bacteria, Gram-negative bacteria and mycoplasma have strong antibacterial activity. Florfenicol is primarily a bacteriostatic agent, by binding to 50S ribosomal subunit, inhibiting bacterial protein synthesis. Florfenicol in vitro antibacterial activity against many microorganisms and chloramphenicol, thiamphenicol similar or stronger, some due to acetylation of chloramphenicol-resistant bacteria, such as E. coli, Klebsiella pneumoniae, Pasteurella multocida, etc. may throw florfenicol sensitive. Hemolytic Pasteurella, Pasteurella multocida and Actinobacillus pleuropneumoniae florfenicol highly sensitive.
Pharmacokinetics of florfenicol oral rapidly absorbed after about 1 hour to reach therapeutic concentrations in the blood, from 1 to 3 hours to reach peak plasma concentration. Bioavailability of more than 80%. Florfenicol is widely distributed in animals, can through the blood-brain barrier. The main original drug from the urine excretion, a small amount of feces.
Indications for sensitive bacteria in pigs, chickens and fish bacterial diseases. For example, hemolytic Pasteurella, kill more porcine Pasteurella and Actinobacillus pleuropneumoniae caused by respiratory infections, typhoid and paratyphoid fever caused by Salmonella, chicken cholera, salmonellosis diseases such as E. coli; fish Pasteurella Vibrio, Staphylococcus aureus, Aeromonas hydrophila, enteritis caused by bacteria of fish bacterial sepsis, enteritis, red skin disease.
Dosage in terms of the product. Oral: per 1kg of body weight, pigs, chickens 0.2 ~ 0.3g 2 times a day, once every 3 to 5 days.
Adverse reactions (1) This product is higher than the recommended dose has some immunosuppressive effects.
(2) embryo toxicity, pregnancy and lactation livestock caution.
[Note] (1) laying on the disabled.
(2) renal insufficiency Huanxu need appropriate reduction or longer dosing intervals.
(3) vaccination or immune function in animals serious defect disabled.
Withdrawal period [20] pig, chicken on the 5th; 375 live fish.
[Specification] 10%.
¡¾Packing¡¿ 100g / bag × 90 bags / box.
[Storage] sealed and kept in a dry place.
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