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Chang Shun

The main components of colistin sulphate.

【Properties】 white or off-white powder.

Pharmacological effects pharmacodynamics peptide antibiotic polymyxin genus, is a basic cationic surfactants, phospholipids and bacterial cell membrane through interaction, to penetrate the bacterial cell membrane, destruction of the structure, thereby causing the membrane permeability changes, resulting in bacterial death, generating a bactericidal effect. The product of aerobic bacteria, E. coli, Haemophilus, Klebsiella, Pasteurella, Pseudomonas aeruginosa, Salmonella, Shigella bacteria Gram-negative bacteria have a strong antibacterial effect on colistin sensitive bacteria produce little resistance. Proteus and Serratia most affected from colistin. Gram-positive bacteria are usually not sensitive.

                        Pharmacokinetics oral administration is hardly absorbed, but parenteral administration is rapidly absorbed. Drug into the body can be quickly distributed into the heart, lungs, liver and skeletal muscle, but not easy to enter the cerebrospinal, pleural, articular lesions and infections. Primarily by renal excretion.

Indications for the prevention and treatment of pigs, chickens and intestinal infections caused by Gram-negative bacteria, such as Piglet dysentery, piglets white diarrhea, piglet paratyphoid fever, salmonellosis, chicken E. coli disease.

Dosage in terms of the product. Mixed drink: every 1L of water, chicken 0.2 ~ 0.6g; spices: pig feed per 1kg of 0.4 ~ 0.8g.

Adverse reactions polymyxin class when taken orally or topically animal well tolerated, systemic application can cause renal toxicity, neurotoxicity, and neuromuscular blocking effects, toxicity polymyxin than polymyxin B Small .

[Note] (1) laying on the disabled.

(2) should not be used continuously for more than a week.

[Withdrawal period] pigs, chickens 7th.

[Specification] 100g: 10g (3 million Units)

【Packing】 100g / bag × 90 bags / box.

[Storage] shading, sealed and stored in a dry place.

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